{"id":1224,"date":"2022-03-08T12:54:00","date_gmt":"2022-03-08T11:54:00","guid":{"rendered":"http:\/\/nudch.eu\/nudch-zavrsil-prvu-etapu-budovania-bunkovej-jednotky"},"modified":"2022-11-25T13:17:46","modified_gmt":"2022-11-25T12:17:46","slug":"nudch-zavrsil-prvu-etapu-budovania-bunkovej-jednotky","status":"publish","type":"post","link":"https:\/\/nudch.eu\/en\/nudch-zavrsil-prvu-etapu-budovania-bunkovej-jednotky","title":{"rendered":"N\u00daDCH zav\u0155\u0161il prv\u00fa etapu budovania bunkovej jednotky"},"content":{"rendered":"

\"\"<\/strong><\/p>\n

Na TJKD v\u00a0minulom roku vykonali spolu 31 alog\u00e9nnych a autol\u00f3gnych transplant\u00e1ci\u00ed<\/strong><\/p>\n

V\u00a0Bratislave 8. marca 2022 – N\u00e1rodn\u00fd \u00fastav detsk\u00fdch chor\u00f4b je o\u00a0krok bli\u017e\u0161ie k\u00a0vybudovaniu nov\u00e9ho pracoviska v\u00a0r\u00e1mci Oddelenia laborat\u00f3rnej medic\u00edny (OLM) – roz\u0161\u00edreniu Krvnej banky o\u00a0\u0161pecializovan\u00e9 pracovisko bunkovej jednotky. \u00a0Bude sl\u00fa\u017ei\u0165 predov\u0161etk\u00fdm pacientom\u00a0Kliniky detskej hematol\u00f3gie a\u00a0onkol\u00f3gie LF UK a\u00a0N\u00daDCH a\u00a0tie\u017e pacientom ostatn\u00fdch klin\u00edk. \u00a0Prv\u00fa etapu budovania tohto pracoviska sa podarilo zav\u0155\u0161i\u0165\u00a0 v\u010faka pomoci Nad\u00e1cie Kvapka n\u00e1deje.<\/strong><\/p>\n

N<\/strong>ov\u00e9 met\u00f3dy a trendy lie\u010dby onkologick\u00fdch ochoren\u00ed st\u00e1le viac vyu\u017e\u00edvaj\u00fa schopnosti \u013eudsk\u00e9ho tela bojova\u0165 s chorobou cez \u010diasto\u010dn\u00e9 upravenie vlastnost\u00ed bielych krviniek. Aby lek\u00e1ri mohli tak\u00fato lie\u010dbu zavies\u0165 pre deti na Slovensku, vznikla potreba \u0161pecializovan\u00e9ho pracoviska. \u00a0 Okrem v\u00fdroby bunkov\u00fdch produktov, z ktor\u00fdch bude m\u00f4c\u0165 by\u0165 vyroben\u00fd “bunkov\u00fd” liek, bude pracovisko pokr\u00fdva\u0165 cel\u00fa logistiku autol\u00f3gnych a alog\u00e9nnych \u0161tepov kostnej drene a perif\u00e9rnych krvotvorn\u00fdch buniek, in\u00fdch bunkov\u00fdch produktov od ich v\u00fdroby, transportu, spracovania, uskladnenia a\u017e po podanie pacientovi..<\/p>\n

Pand\u00e9mia ochorenia COVID \u2013 19 ovplyvnila aj transplant\u00e1ciu krvotvorn\u00fdch buniek a\u00a0mnoh\u00e9 in\u00e9 ochorenia.\u00a0 K\u00fdm pred pand\u00e9miou sa v\u00e4\u010d\u0161inou pou\u017e\u00edvali \u010derstv\u00e9 \u0161tepy krvotvorn\u00fdch kme\u0148ov\u00fdch buniek, v\u00a0s\u00fa\u010dasnosti sa\u00a0 zmrazuj\u00fa, aby sa vyl\u00fa\u010dilo riziko, \u017ee die\u0165a kv\u00f4li COVID-19 nem\u00f4\u017ee vst\u00fapi\u0165 do transplanta\u010dn\u00e9ho programu. ,,Pre ve\u013ek\u00fa nevyspytate\u013enos\u0165 ochorenia darcu alebo pacienta na COVID-19 sa zvolil postup skor\u0161ieho nazbierania \u0161tepov, ich n\u00e1sledn\u00e9 spracovanie a\u00a0zamrazenie pred spusten\u00edm pr\u00edpravn\u00e9ho re\u017eimu transplant\u00e1cie. Takto sme mali istotu, \u017ee po napl\u00e1novan\u00ed transplant\u00e1cie nebude darca vyraden\u00fd z darcovstva pre chorobu a teda budeme ma\u0165 pre pacienta prichystan\u00fd \u0161tep. T\u00e1to situ\u00e1cia v\u0161ak sp\u00f4sobila ve\u013ek\u00fd n\u00e1por na \u0161pecializovan\u00e9 zariadenia, ktor\u00e9 bunkov\u00e9 produkty sprac\u00favaj\u00fa. Ma\u0165 tak\u00e9to \u0161pecializovan\u00e9 pracovisko n\u00e1m umo\u017en\u00ed spracova\u0165 a uskladni\u0165 \u0161tepy krvotvorn\u00fdch buniek a bunkov\u00fdch produktov. Nov\u00e9 priestory \u0161pecializovan\u00e9ho laborat\u00f3ria n\u00e1m umo\u017enia pracova\u0165 s bunkami v bezpe\u010dnom prostred\u00ed, v\u010faka \u010domu m\u00f4\u017eeme zvoli\u0165 pre na\u0161ich pacientov vhodnej\u0161ie alternat\u00edvne sp\u00f4soby odberov krvotvorn\u00fdch buniek, ale aj in\u00fdch \u0161pecializovan\u00fdch typov najmodernej\u0161ej bunkovej lie\u010dby,\u201c <\/em>hovor\u00ed MUDr. Tom\u00e1\u0161 S\u00fdkora<\/strong>, PhD. lek\u00e1r TJKD.<\/p>\n

,,Aj toto je jeden z\u00a0d\u00f4vodov, pre\u010do sa zvy\u0161uje potreba ma\u0165 tak\u00e9to\u00a0 pracovisko priamo v\u00a0na\u0161ej nemocnici. \u0160tepy krvotvorn\u00fdch kme\u0148ov\u00fdch buniek na transplant\u00e1ciu maj\u00fa \u017eivotnos\u0165\u00a0 len 72 hod\u00edn, \u010do znamen\u00e1, \u017ee od pr\u00edpravy do podania prij\u00edmate\u013eovi alebo definit\u00edvneho spracovania \u0161tepu nem\u00f4\u017ee prejs\u0165 dlh\u0161\u00ed \u010das. Dobudovanie nov\u00e9ho pracoviska n\u00e1m umo\u017en\u00ed \u0161tepy nielen bezpe\u010dne uskladni\u0165 do doby pou\u017eitia, ale aj technologickou \u00fapravou \u0161tepu priamo na na\u0161om pracovisku zabezpe\u010di\u0165 bezpe\u010dnej\u0161ie transplant\u00e1cie,\u201c <\/em>ocenil v\u00fdznam nov\u00e9ho pracoviska MUDr. Peter Barto\u0148,<\/strong> riadite\u013e N\u00daDCH a\u00a0po\u010fakoval Nad\u00e1cii Kvapka n\u00e1deje za pomoc nielen pri budovan\u00ed tohto pracoviska, ale aj za dlhodob\u00fa podporu nemocnice.<\/p>\n

V\u00fdznam\u00a0 nov\u00e9ho kroku vyzdvihuje aj prednostka KDHaO, prof. MUDr. Alexandra Kolenov\u00e1, PhD.:<\/strong> \u201eTransplanta\u010dn\u00e1 jednotka KDHaO N\u00daDCH je jedine\u010dn\u00fdm centrom pre detsk\u00fdch pacientov v\u00a0r\u00e1mci Slovenska. V\u010faka v\u00fdborn\u00fdm v\u00fdsledkom lie\u010dby, ktor\u00e9 dlhodobo dosahuje, patr\u00ed medzi \u0161pi\u010dkov\u00e9 Eur\u00f3pske centr\u00e1.\u00a0 Na transplant\u00e1ciu kostnej drene s\u00fa indikovan\u00ed len t\u00ed detsk\u00ed pacienti, u\u00a0ktor\u00fdch boli vy\u010derpan\u00e9 v\u0161etky in\u00e9 lie\u010debn\u00e9 mo\u017enosti. Je nevyhnutn\u00e9, aby sme dr\u017eali krok s\u00a0vedeck\u00fdm pokrokom,\u00a0 v\u00a0N\u00daDCH neust\u00e1le zlep\u0161ovali podmienky a\u00a0umo\u017enili tak,\u00a0 aby na\u0161i detsk\u00ed pacienti na Slovensku dost\u00e1vali najmodernej\u0161iu lie\u010dbu.\u201c<\/em><\/p>\n

,,Sme radi, \u017ee zav\u0155\u0161en\u00edm a\u00a0odovzdan\u00edm prvej etapy nov\u00e9ho pracoviska vieme otvori\u0165 nov\u00e9 okno v\u00a0lie\u010dbe pri \u017eivot zachra\u0148uj\u00facich transplant\u00e1ci\u00e1ch krvotvorn\u00fdch buniek a\u00a0zv\u00fd\u0161i\u0165 \u0161tandard a\u00a0komfort lie\u010dby. Ver\u00edme, \u017ee toto pracovisko spln\u00ed v\u0161etky po\u017eiadavky aj z\u00a0h\u013eadiska pr\u00edsnych medzin\u00e1rodn\u00fdch predpisov. Chceme z\u00e1rove\u0148 po\u010fakova\u0165 v\u0161etk\u00fdm darcom, fyzick\u00fdm aj pr\u00e1vnick\u00fdm osob\u00e1m, v\u010faka ktor\u00fdm m\u00f4\u017eeme dnes odovzda\u0165 nov\u00e9 pracovisko najv\u00e4\u010d\u0161ej detskej nemocnici na Slovensku<\/em>,\u201c povedal \u0160tefan Bern\u00e1t, <\/strong>spr\u00e1vca Nad\u00e1cie Kvapka n\u00e1deje.<\/p>\n

\u0160tepy krvotvorn\u00fdch kme\u0148ov\u00fdch buniek sa musia upravi\u0165 <\/strong><\/p>\n

,,\u0160tepy krvotvorn\u00fdch kme\u0148ov\u00fdch buniek v s\u00fa\u010dasnosti\u00a0 spracov\u00e1vame v\u00a0spolupr\u00e1ci s\u00a0partnersk\u00fdmi pracoviskami,\u201c <\/em>povedal MUDr. Peter \u0160vec,<\/strong> PhD., prim\u00e1r Transplanta\u010dnej jednotky kostnej drene TJKD) Kliniky detskej hematol\u00f3gie a\u00a0onkol\u00f3gie\u00a0 (KDHaO) LF UK a\u00a0N\u00daDCH a\u00a0\u010falej vysvetlil, ako a\u00a0pre\u010do sa odobrat\u00e9 \u0161tepy musia upravova\u0165: ,,\u0160tep odober\u00e1me z\u00a0kostnej drene alebo perif\u00e9rnej krvi a\u00a0m\u00e1 ur\u010dit\u00e9 zlo\u017eenie. Pre transplant\u00e1ciu s\u00fa ur\u010dit\u00e9 bunky v\u00a0nadbytku, najm\u00e4 u\u00a0det\u00ed. Pre optim\u00e1lny priebeh transplant\u00e1cie by sme ich potrebovali menej a\u00a0niektor\u00e9 tie\u017e m\u00f4\u017eu by\u0165\u00a0 potenci\u00e1lne agres\u00edvne vo\u010di prij\u00edmate\u013eovi. Pomocou nov\u00fdch technol\u00f3gi\u00ed na \u00fapravu \u0161tepu, na ktor\u00fdch implement\u00e1ciu v bud\u00facnosti je nov\u00e9 pracovisko pripraven\u00e9, budeme m\u00f4c\u0165\u00a0 nadbyto\u010dn\u00e9 bunky zredukova\u0165 a\u00a0z\u00e1rove\u0148 zachova\u0165 obsah z\u00e1rodo\u010dn\u00fdch krvotvorn\u00fdch buniek, ktor\u00e9 potrebujeme.\u201c <\/em><\/p>\n

Nov\u00e9 technologick\u00e9 vybavenie umo\u017en\u00ed technicky spracova\u0165 ve\u013emi ve\u013ea r\u00f4znych druhov \u013eudsk\u00fdch buniek a\u00a0tkan\u00edv a\u00a0otv\u00e1ra nov\u00e9 mo\u017enosti lie\u010dby. \u00a0Lie\u010dba niektor\u00fdch deti vy\u017eaduje, \u017ee v\u00a0ur\u010ditom obdob\u00ed lie\u010debn\u00e9ho protokolu lek\u00e1ri zozbieraj\u00fa ich krvotvorn\u00e9 bunky a zamrazia ich na neskor\u0161ie obdobie lie\u010dby, kedy ich bud\u00fa potrebova\u0165. ,,Napr\u00edklad deti lie\u010den\u00e9 na n\u00e1dorov\u00e9 ochorenia, ktor\u00e9\u00a0 potrebuj\u00fa vysokod\u00e1vkov\u00fa chemoterapiu, dostan\u00fa po chemoterapii svoje krvinky na r\u00fdchlu obnovu krvotvorby. V\u00a0minulosti sme neraz t\u00fato lie\u010dbu museli prisp\u00f4sobova\u0165 kapacite partnersk\u00e9ho pracoviska, aby n\u00e1m vedeli produkty spracova\u0165. Z\u00e1rove\u0148 d\u00fafame, \u017ee vybudovan\u00edm tohto pracoviska sa n\u00e1m otvoria nov\u00e9 mo\u017enosti pr\u00e1ce s\u00a0bunkov\u00fdmi \u0161tepmi,\u201c <\/em>hovor\u00ed \u010falej prim\u00e1r TJKD, Peter \u0160vec.<\/p>\n

Aktu\u00e1lne na Slovensku m\u00e1me dostupn\u00e9 met\u00f3dy, ktor\u00e9 zabezpe\u010duj\u00fa odbery buniek a krvotvorn\u00fdch buniek u v\u00e4\u010d\u0161iny detsk\u00fdch pacientov. Nov\u00e9 mo\u017enosti sa otv\u00e1raj\u00fa aj pre pacientov s\u00a0n\u00edzkou hmotnos\u0165ou, pre ktor\u00fdch t\u00fato mo\u017enos\u0165 nevieme pon\u00faknu\u0165 a je nutn\u00e9, aby kv\u00f4li nej cestovali do zahrani\u010dia. Nov\u00e9 pracovisko bude ma\u0165 ve\u013ek\u00fd v\u00fdznam pr\u00e1ve pre t\u00fato skupinu pacientov. Patria medzi nich detsk\u00ed onkologick\u00ed pacienti, ale aj detsk\u00ed pacienti po transplant\u00e1cii bojuj\u00faci s chorobou \u0161tepu proti hostite\u013eovi.<\/p>\n

Nad\u00e1cia Kvapka n\u00e1deje<\/strong> zabezpe\u010dila realiz\u00e1ciu projektu z\u00a0prostriedkov z\u00edskan\u00fdch z\u00a0verejnej zbierky a\u00a0realiz\u00e1cia si vy\u017eiadala sumu celkom: 312.875,- EUR, v\u00a0ktorej s\u00fa zahrnut\u00e9 n\u00e1klady na projekty, stavebn\u00e9 \u00fapravy, vybudovanie klimatiz\u00e1cie, pr\u00edstrojov\u00e9 vybavenie a\u00a0celkov\u00e9 zariadenie priestorov nov\u00e9ho oddelenia.<\/p>\n","protected":false},"excerpt":{"rendered":"

Na TJKD v\u00a0minulom roku vykonali spolu 31 alog\u00e9nnych a autol\u00f3gnych transplant\u00e1ci\u00ed V\u00a0Bratislave 8. marca 2022 – N\u00e1rodn\u00fd \u00fastav detsk\u00fdch chor\u00f4b je o\u00a0krok bli\u017e\u0161ie k\u00a0vybudovaniu nov\u00e9ho pracoviska v\u00a0r\u00e1mci Oddelenia laborat\u00f3rnej medic\u00edny (OLM) – roz\u0161\u00edreniu Krvnej banky o\u00a0\u0161pecializovan\u00e9 pracovisko bunkovej jednotky. \u00a0Bude sl\u00fa\u017ei\u0165 predov\u0161etk\u00fdm pacientom\u00a0Kliniky detskej hematol\u00f3gie a\u00a0onkol\u00f3gie LF UK a\u00a0N\u00daDCH a\u00a0tie\u017e pacientom ostatn\u00fdch klin\u00edk. \u00a0Prv\u00fa etapu […]<\/p>\n","protected":false},"author":8,"featured_media":3457,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[78],"tags":[],"yoast_head":"\nN\u00daDCH zav\u0155\u0161il prv\u00fa etapu budovania bunkovej jednotky | National Institute of Children\u2019s 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